Biological Exploration I - bmc.BIOL.B110.merged.F22
Section outline
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Biology 110 is an introductory-level course designed to encourage students to explore the field of biology at multiple levels of organization: molecular, cellular, organismal and population. Each course will explore these areas of biology through a unifying theme. In Fall 2022, Biology 110 will explore the ways the central dogma of molecular biology relates to the biochemical basis of human disease through the lens of biochemistry, cell biology, genetics and molecular biology. The laboratory portion of the course will explore the fundamentals of molecular and cellular biology through scientific research, with an emphasis on scientific process and experimental design. Topics include genetically modified organisms, stem cell biology, and molecular biological techniques.
Course Learning Goals:
- Students will gain foundational knowledge in biology, with an emphasis in the sub-disciplines of cell biology, genetics & molecular biology, by learning basic principles of the field and how these basic principles were derived.
- Students will become familiar with various methodological approaches used to investigate biological questions.
- Students will develop skills required to synthesize information and apply their knowledge to new situations.
- Students will make connections among the different sub-disciplines of biology, as well as to disciplines outside of biology.
Important information about this course:
- Lectures will be held in Carpenter B21.
- Section 001 meets MWF from 10:10 am - 11 am.
- Section 002 meets MWF from 11:10 am - noon.
- Students are expected to attend lecture in person unless they are ill. Lectures are being recorded in case of extended illness or injury, and students in this situation are encouraged to reach out to obtain access to recordings.
- Instructors:
- Dr. Michelle Kanther -- office: Park Science 210; email: mkanther@brynmawr.edu; schedule office hours appointments here.
- Dr. Tamara Davis -- office: Park Science 222; email: tdavis@brynmawr.edu; Dr. Davis’s office hours: Tuesdays, 8-9 pm (Zoom link below); Wednesdays, 12:30-2 pm, Park Science room 363C. Office hours for Dr. Davis will start when she starts teaching: Wednesday, Sept 28th.
- TA office hours:
- Wednesdays, 7-8 pm; Park Science room 227.
- Thursdays, 6-8 pm; Park Science room 363C.
- Sundays, 7-8 pm; Park Science room 227.
- The laboratory component for this course is taught by Dr. Michelle Kanther (M,T,W,F afternoons) and Sadie Marlow (T evening) and has its own Moodle page. Students must enroll in and attend one laboratory section each week; sections meet at the following times: Monday, 1:10 - 4 pm; Tuesday, 1:40 - 4:30 pm; Tuesday, 7:10 - 10 pm; Wednesday, 1:10 - 4 pm; Friday, 1:10 – 4 pm.
- Recommended textbook for the course: Campbell Biology, 11th (2018) or 12th (2021) edition, Pearson. Four copies of the 11th edition and two copies of the 10th edition are on reserve at Collier library.
- Homework assignments, supplemental readings, etc. are ONLY found on the Moodle site; be sure to check Moodle regularly!
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Course Introduction
Scientific Inquiry
Chemistry of Life -
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Chemistry of Life, continuedMacromolecules
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Cells & organelles
Cell Cycle & Signalling
Cell Membranes & Metabolism -
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Cellular Respiration & Fermentation
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Exam I Review session (Monday)
Mendelian genetics & concepts of dominance
Pedigrees, transmission patterns & probability-
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Pedigrees, transmission patterns and probabilities, continued
Cancer genetics
Case study: genetics of familial cancer
note: there will not be an in-person class meeting on Wednesday, October 5th -- watch the pre-recorded lecture between Tuesday & Friday this week!-
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Meiosis, independent assortment & linkage
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Extensions to Mendelian genetics: epistasis & polygenic traits
Population genetics -
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DNA is the genetic material
Discussion: eugenics (Friday)-
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DNA structure & replication
Transcription-
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Translation
Mutations
Misfolded proteins & prions -
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Gene regulation
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Discussion: Bioethics
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