Section outline

  • A survey of topics related to drug discovery including lead discovery, target interactions, structural optimization, drug metabolism and drug synthesis.  The course will engage in an advanced treatment of these topics with particular attention to an understanding of drug design and development on the molecular level. Case studies will be used to illustrate the application of these principles. 


    • Announcements Forum
    • Medicinal Chemistry Fall 2026 syllabus File PDF

      This will likely transform your life into a paradise of drug-induced good health.

      -updated 9-1-26

      281.6 KB · Uploaded 09/1/26, 17:36
    • What you should know before taking Medicinal Chemistry File PDF

      You should have familiarity with these topics and therefore I will assume that I don't need to elaborate on these subjects when we encounter them. 

      I suspect most of you've had very little coverage of heteroaromatics, which are a common component of many small molecule drugs, so I will likely provide some background early in the course. 

      786.5 KB · Uploaded 08/25/26, 16:56
    • Calendly link for 1-on-1 meetings URL

      If you'd like to meet with Dr. Mal for a 1-on-1 (or 1-on-X with fellow PB's in your study group), please follow the Calendly link to schedule a meeting time in Park 270, Dr. Mal's office. The appointments are for 20 minutes.

    • Useful compilation of medicinal chemistry terms File PDF

      This may or may not be useful for your studies of the medicinal chemistry literature. A lot of it deals with drug metabolism issues, which are extremely important, and will be discussed in the first few weeks of lectures. 

      3.9 MB · Uploaded 08/25/26, 16:56